[BR]Diabetes as Psoriasis Treatment Fall-out?
from Randy C.
[BR]Dear Ed: You mentioned in one of your "briefings"
a few months ago that you had been diagnosed Type 1 diabetic (insulin dependent),
and then you said in a subsequent issue [of Flake HQ] that you had been
using powerful topical steroids for many years. Have you asked your doctors
about the possible connection? I ask because I, too, am diabetic (type 2,
non-insulin dependent) and also used rub-on medicines for psoriasis for
years before I got diabetes. I've read there is some evidence that overuse
of steroids can trigger diabetes. -Randy
*****
[BR]Ed's Reply:
[BR]Randy, I read about that connection, too—I think in
some recent NPF literature. I mentioned this to both my derm and my diabetes
doctor. Both responses were grunt-like. The similarities between the "pathologies"
of diabetes and psoriasis are interesting.
[BR]1. A genetic proclivity is suspected for both diseases.
2. Both appear to be "triggered."
3. Neither is curable.
4. Both are expensive to control.
[BR]Pragmatically, there's no way my dermatologist is going
to say over-use of topical corticosteroids caused my diabetes. Duh! My diabetes
doctor's attitude was to simply stop inquiring when she learned there was
a history of the disease in my family (maternal grandfather died of complications
stemming from diabetes). So the question is pretty much rhetorical as far
as the pros are concerned.
[BR]Still, from a personal angle, I've thought a lot about
it. My use of topical corticosteroids has escalated significantly over the
past seven years, concurrent with the spread of lesions from 0% of my skin
surface to 60+% at its worst. And it would be difficult for my derm to be
truly cognizant of the amount I use because it varies by the season of the
year and, by chance, the prescript usually come up for renewal at the end
of a "light" season. If he kept a running tally of the amount
of medicines I use over a year—or over the course of my disease—he
would see a different picture than he might see by looking at the most current
two or three pages of my file.
[BR]I'm sure there's also a diminishment of concern in my case
because I DO use the corticosteroids on a revolving regimen that cycles
from low-potency to high-potency formulas. When this cycle is in sync with
the seasons there's no problem, but if I happen to flame at a time when
I'm using a low-potency potion, I just use more of it. When it comes to
building up potentially toxic levels of steroids in my skin, what's the
difference between using a low-potency formulation three times a day or
a high-potency formulation once a day?
[BR]Not to let my derm off the hook so easily, let me also
say I've wondered why, for three+ years now, he hasn't bothered to actually
LOOK AT my psoriasis. He sees my hands and one calf (usually because I show
him without prompting) once a year. He hasn't asked to see the rest of me
for at least three years. There has never been a blood work-up intended
to reveal steroid artifacts. The only blood work-up my derm has ever ordered
prefaced his intent to get me on methotrexate. This was in 1992 or 1993.
Elevated liver enzymes nixed that idea. There was an incidental indication,
in 1994 or 1995, that I was systematizing steroids from direct intralesion
injections: lesions NOT injected were improving right along with those that
WERE, suggesting to my derm that my blood was distributing the steroid (not
good).
[BR]So, yes, I harbor a shadowy belief that somehow my psoriasis
treatment regimen has contributed to the triggering of my diabetes. But
given the myriad other ways I've abused my health throughout my adult life,
that belief can never be factually validated. By all rights my tombstone
should read: "Here lies Ed Dewke | Killed by Many People | But Mostly
By Himself." -Ed 作者: 白开水 时间: 2008-4-17 00:25
[BR]看不懂，谁翻译。作者: 水精灵 时间: 2015-2-10 01:28
<p>今天翻开此贴真得很无奈。我去年确诊糖尿病。复外医院让我住院，没干。我知道几个老病友都有。甚至毛的女儿李纳银病好了，但有糖尿病很多年，靠打胰岛素控制。我的另一朋友也是二十几岁银病好了，在三十几岁得糖尿病，也是靠注射控制。我的银没好，又先后来了血压高，血脂高。去年加上血糖高。难道这就是我一个人的宿命？<br/>我做到的一点八年没吃西药降压，没吃他丁降脂，没用胰岛素。</p>作者: _珍惜 时间: 2015-2-10 12:13
糖尿病不见得和牛皮癣有关吧。饮食生活不规律都是有关系的。我29,我27岁判断我是糖尿病前期。医生说我不治疗以后发展就是糖尿病,医生也是让我吃了一种药吃了3个月后我坚持停药靠锻炼。锻炼的话一般也能控制住。这是免疫机能导致的代谢问题。代谢好了就不会有糖尿病。人随着年纪的增长,免疫机能是会有所下降。所以需要多锻炼