尝试辅助疗法---- 富马酸

话说我泡盐浴也是1年光景。 可见我原来的发帖。泡澡纪录片。

从3月份开始基本效果不是特别的明显，用网友回帖的话说就是动态平衡。 去皮屑还是有一定效果的，
就是癣的面积几乎没有什么缩小。

在国外网站查了很久，查到现在国外用 小剂量的 Fumaric acid （延胡索酸）来治疗此病，看似效果还行。

我理解是病人细胞新陈代谢的力度不够，所以皮肤产生皮屑，而延胡索酸主要就是促进新陈代谢的。
理解错了，大家也别骂人，我的知识是很有限的，我有自知自明。

（我不想被人满帖子谩骂质疑，所以大家别问我太多，我也帮不了任何。

    ！！我自己不卖药也不推荐卖药的也会不推荐医生！！

如果有效果的话， 我会上照片，这至少是个思路， 没效果的话，我就当次小白鼠吧。
我， 没吃过中药治疗，没用过激素治疗，煤焦油是我少量用过的涂剂）

希望还是有的。。。至少还能打生物制剂呢 。。。就是现在贵了一点。
不过价格便宜下来就是时间的问题。



付百科上拷贝过来的内容 （英文的稍微详细些）
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延胡索酸，又名富馬酸、紫堇酸或地衣酸（IUPAC名為反-丁烯二酸），是一種無色、易燃的晶體，由丁烯衍生出的羧酸。它的化學式是C4H4O4。燃燒延胡索酸會釋出帶有刺激性的順丁烯二酐煙燻。它的味道像水果，並在延胡索屬、牛肝菌屬、地衣及冰島海苔中可以發現。

延胡索酸用于製造聚酯樹脂及多元醇，以及作為染料的媒染劑或是調味料。它是一種普遍的食物添加劑及膳食補充劑，且有時在飲料或發酵粉中作為酒石酸的代用物。

[编辑] 生物學與馬來酸相關，細胞會用延胡索酸來從食物中產生能量。人類皮膚在日光下亦會自然產生延胡索酸。

[编辑] 藥物由於有指牛皮癬的病因是皮膚在產生延胡索酸的缺憾，所以延胡索酸酯有時會受作治療這病症。在開始時劑量為每日60-105mg，而其後逐步增加至每日1,290mg。使用延胡索酸的副作用包括腎臟或消化系統疾病，及皮膚及紅等，這是因過度服用所致。在長期使用後，會出現白血球減少的現象。
食物自1946年開始，因延胡索酸的無毒性，被用作一種食物酸化劑。它廣泛的使用在著重純度的飲料及發酵粉，如威路士提子汁。一般亦會用作酒石酸的代用物，或有時會取代檸檬酸。若要保持與檸檬酸一樣的味道，延胡索酸與檸檬酸的比例為0.91g比1.36g。
BiologyFumaric acid is found in fumitory (Fumaria officinalis), bolete mushrooms (specifically Boletus fomentarius var. pseudo-igniarius), lichen, and Iceland moss.

Fumarate is an intermediate in the citric acid cycle used by cells to produce energy in the form of adenosine triphosphate (ATP) from food. It is formed by the oxidation of succinate by the enzyme succinate dehydrogenase. Fumarate is then converted by the enzyme fumarase to malate. Human skin naturally produces fumaric acid when exposed to sunlight.[citation needed]

Fumarate is also a product of the urea cycle.



MedicineFumaric acid esters are used to treat psoriasis, as it has been suggested that the condition is caused by an impairment of fumaric acid production in the skin.[1] [2]A starting dose is 60-105 mg daily, which may be gradually increased to as much as 1,290 mg per day. Side effects include kidney or gastrointestinal disorders, as well as skin flushing; these are mainly caused by excess intake. Decreased white blood cell (WBC) counts have been reported with prolonged use.[citation needed]

A fumaric acid ester is currently under investigation for treatment of multiple sclerosis

FoodFumaric acid is a food acidulent used since 1946. It is non-toxic. It is generally used in beverages and baking powders for which requirements are placed on purity. It is generally used as a substitute for tartaric acid and occasionally in place of citric acid, at a rate of 1.36 g of citric acid to every 0.91 grams of fumaric acid to add sourness, similar to the way malic acid is used. It is also used as a coagulant in stovetop pudding mixes.

ChemistryFumaric acid was first prepared from succinic acid.[3] A traditional synthesis involves oxidation of furfural (from the processing of maize) using chlorate in the presence of a vanadium-based catalyst.[4] Currently, industrial synthesis of fumaric acid is mostly based on catalytic isomerisation of maleic acid in aqueous solutions at low pH. Maleic acid is accessible in large volumes as a hydrolysis product of maleic anhydride, produced by catalytic oxidation of benzene or butane.[5]

The chemical properties of fumaric acid can be anticipated from its component functional groups. This weak acid forms a diester, it undergoes additions across the double bond, and it is an excellent dienophile.

Fumaric acid does not combust in a bomb calorimeter under conditions where maleic acid deflagrates smoothly. For teaching experiments designed to measure the difference in energy between the cis- and trans- isomers, a measured quantity of carbon can be ground with the subject compound and the enthalpy of combustion computed by difference.



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[此贴子已经被作者于2012-3-5 5:53:42编辑过]

很多年前我见有报道说是富什么的药物能治疗P，可这些年过来，没见人怎么说啊。。。

楼主以前的帖子我看过，单纯用盐水泡澡并没有那么神奇的效果，我也是这个体会。
感谢楼主，不管是否有效果，希望楼主一定要告诉大家。

 不是皮肤新陈代谢力度不够，是力度太强才导致脱屑，正常皮肤是20几天，我们是3-4天、

 不知道以前什么样，照片看你的面积不小，好在不是特别红，擦点外用药应该可以了、

上来冒个泡吧， 8月开始尝试新疗法，盐浴停了，一是为了每天节约一个小时的时间，
二是发现皮肤开始出现干燥的情况，感觉和盐浴有关。

1个半月的时间， 让照片说话吧。

[此贴子已经被作者于2011-9-18 22:45:46编辑过]

以前的泡澡贴:

http://www.yxb365.com/bbs/dispbbs.asp?BoardID=12&ID=47733&replyID=70166&skin=1

我坚持了一年。 到今天8月份停了。

[此贴子已经被作者于2011-12-3 4:01:31编辑过]

我觉的是有效果的。 平了 。

是用来泡澡吗？

看上去好多了，但离痊愈还遥远，继续努力，祝你早日康复！
对我们来说，也多了一份希望。
继续关注你的进展。